Ascorbyl Tetraisopalmitate

Cas No.: 183476-82-6 INCI : ASCORBYL TETRAISOPALMITATE Appearance : Colorless to pale yellow transparent liquid Molecular Formula :C70H128O10 Molecular Weight :1129.76

Oil-Soluble Vitamin C Innovation – Superior Penetration & Next-Generation Antioxidant Performance

Ascorbyl Tetraisopalmitate (VCIP) is a cutting-edge oil-soluble Vitamin C derivative designed to deliver exceptional stability, deep skin penetration, and powerful antioxidant activity. It represents a breakthrough in Vitamin C technology, overcoming the limitations of traditional water-soluble forms.

1. Product Introduction

Ascorbyl Tetraisopalmitate is an advanced esterified derivative of Vitamin C, widely recognized as a next-generation active ingredient in cosmetic formulations. Commonly abbreviated as VCIP (Vitamin C Tetra-Isopalmitate), it is known for its superior stability and lipid compatibility.

This ingredient has received significant international recognition. It was approved as a pharmaceutical-grade material by the Japanese Ministry of Health, Labour and Welfare in 2006, recognized as a functional whitening agent in Korea, and listed among officially approved whitening ingredients by Taiwan health authorities.

2. Cosmetic Functions

  • Skin brightening and tone correction

  • Reduction of dark spots and hyperpigmentation

  • Powerful antioxidant protection against environmental stress

  • Moisturizing and skin conditioning

With a low irritation profile, it is considered safe for most skin types and is non-comedogenic, making it suitable for daily skincare formulations.

3. Key Efficacy & Benefits

  • Exceptional Stability: Resistant to oxidation compared to traditional Vitamin C

  • Oil-Soluble & Skin-Affinitive: Easily integrates into lipid layers for enhanced absorption

  • Deep Penetration: Effectively delivers active benefits into deeper skin layers

  • Brightening Effect: Inhibits tyrosinase activity to reduce melanin formation

  • Anti-Aging: Promotes collagen synthesis and reduces the appearance of wrinkles

  • Anti-Inflammatory: Helps soothe acne-prone and irritated skin

  • Antioxidant Protection: Neutralizes free radicals and prevents premature aging

4. Suitable Skin Types

  • Dry skin

  • Oily skin

  • Sensitive/tolerant skin

  • Pigmented skin

  • Aging and wrinkled skin

  • Skin lacking firmness

5. Formulation Guidelines

  • Recommended pH: Below 6.0 for optimal stability (can extend to pH 7.0 with stabilizers)

  • Addition Phase: Oil phase incorporation recommended

  • Processing: Avoid prolonged exposure to temperatures above 80°C

  • Stability Enhancement: Use chelating agents (e.g., EDTA) and antioxidants (e.g., tocopherol)

  • System Optimization: Add suitable surfactants to prevent oxidation in emulsions

6. Synergistic Compatibility

  • Works effectively with Vitamin E (tocopherol)

  • Compatible with squalane and plant oils

  • Enhances performance with essential fatty acids such as linoleic acid

7. Application Areas

  • Oil-Based Serums: High-performance brightening formulations

  • Creams & Lotions: Stable, non-discoloring emulsions

  • Sunscreen & After-Sun Care: UV protection and repair support

  • Facial Oils & Lip Products: Ideal for oil-based systems

  • Makeup & Primers: Prevents oxidation and dullness in foundation

Why Choose Ascorbyl Tetraisopalmitate (VCIP)?

As a benchmark ingredient among oil-soluble Vitamin C derivatives, VCIP is widely adopted by leading global cosmetic brands. It enables Vitamin C to transcend water-solubility limitations, delivering superior efficacy through lipid-based penetration.

Brand Statement

VCIP allows Vitamin C to move beyond boundaries—penetrating deeply into the skin in its most stable, effective form, revealing a brighter, healthier, and revitalized complexion.

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